ATI TEAS Science Practice Test 2025: 120 High-Yield Questions, Detailed Rationales, and Expert Answer Explanations

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Ace the ATI TEAS Science Exam 2025 with 120 high-yield practice questions, detailed rationales, and expert answer explanations.
Excel in the Science section of the ATI TEAS Exam 2025 with this targeted practice test, designed specifically for nursing and allied health students aiming for top performance. This resource features 120 high-yield practice questions that closely align with the exam’s science domains, including anatomy and physiology, biology, chemistry, and scientific reasoning. Each question is accompanied by detailed rationales and expert answer explanations, providing clarity on complex topics, reinforcing key concepts, and enhancing critical thinking skills. Fully aligned with the 2025 ATI TEAS content outline, this practice test incorporates the latest evidence-based standards and real-world applications to ensure exam readiness. It also includes strategic guidance to improve time management and tackle challenging question formats with confidence. Perfect for students seeking to boost their science scores and secure admission to competitive healthcare programs, this practice test is a vital tool for academic success.
Preview
1. Which of the following helps to prevent pathogens from invading the body?
A) Histamines
B) Mucus ✅
C) T-cells
D) Macrophages
Rationale: Mucus, along with skin and secretions, serves as the body’s first line of defense
by trapping pathogens before they can enter the body. T-cells and macrophages are part of
the adaptive and innate immune responses, respectively, but they act after an infection has
already occurred.
2. A bacterial cell enters the body through a cut in the skin. Which of the following
describes the immune response that would occur next?
A) Cytotoxic T-cells
B) Helper T-cells are activated
C) Histamines are released ✅
D) Antigens are released
Rationale: When a pathogen breaches the skin, the body’s immediate response is the
release of histamines, which trigger inflammation and increase blood flow to the affected
area, bringing immune cells to fight the infection. Antigens are components of the
pathogen, not something the body releases.
3. Which of the following types of cells produce antibodies?
A) T-cells
B) Plasma cells ✅
C) Memory cells
D) Macrophages
Rationale: Plasma cells, derived from activated B-cells, are responsible for producing
antibodies that target specific pathogens. Memory cells store information about previous
infections but do not produce antibodies directly.
4. Which of the following best describes the purpose of a vaccine?
A) To produce extra inflammatory responses such as the release of histamines
B) To practice passive immunity
C) To produce antibodies in case of future infection ✅
D) To increase macrophage production
Rationale: Vaccines introduce weakened or inactive antigens to stimulate an immune
response, leading to antibody production. This prepares the immune system for future
encounters with the pathogen. Passive immunity involves receiving antibodies from
another source, like through breast milk.

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