Duke University School of Nursing 2025 HESI Pharmacology Practice Test: Comprehensive Nursing Exam Questions with Accurate Rationales and Study Support for Guaranteed Success

• Includes 80+ comprehensive pharmacology questions with accurate rationales.
• Covers key topics: drug classifications, dosages, side effects, and nursing interventions.
• Provides study support with detailed explanations and learning resources.
• Features realistic scenarios to connect pharmacology concepts to clinical practice.
• Aligned with Duke University School of Nursing’s curriculum standards.
• Supports HESI and NCLEX-RN preparation with focused remediation tools.
• Offers insights into the 2025 HESI Pharmacology Exam format.

Preview

1.) Ketoconazole is prescribed for a client with a diagnosis of candidiasis. Select the
interventions that the nurse includes when administering this medication. Select all
that apply.
1. Restrict fluid intake.
2. Instruct the client to avoid alcohol.
3. Monitor hepatic and liver function studies.
4. Administer the medication with an antacid.
5. Instruct the client to avoid exposure to the sun.
6. Administer the medication on an empty stomach. – – correct ans- -2. Instruct the
client to avoid alcohol.
3. Monitor hepatic and liver function studies.
5. Instruct the client to avoid exposure to the sun.
Rationale:
Ketoconazole is an antifungal medication. It is administered with food (not on an empty
stomach) and antacids are avoided for 2 hours after taking the medication to ensure
absorption. The medication is hepatotoxic and the nurse monitors liver function
studies. The client is instructed to avoid exposure to the sun because the medication
increases photosensitivity. The client is also instructed to avoid alcohol. There is no
reason for the client to restrict fluid intake. In fact, this could be harmful to the client.
2.) A client with human immunodeficiency virus is taking nevirapine (Viramune). The
nurse should monitor for which adverse effects of the medication? Select all that apply.
1. Rash
2. Hepatotoxicity
3. Hyperglycemia
4. Peripheral neuropathy
5. Reduced bone mineral density – – correct ans- -1. Rash
2. Hepatotoxicity
Rationale:
Nevirapine (Viramune) is a non-nucleoside reverse transcriptase inhibitors (NRTI) that is
used to treat HIV infection. It is used in combination with other antiretroviral
medications to treat HIV. Adverse effects include rash, Stevens-Johnson syndrome,
hepatitis, and increased transaminase levels. Hyperglycemia, peripheral neuropathy,
and reduced bone density are not adverse effects of this medication.